Macrophages are exploited from an innate wound healing response to facilitate cancer metastasis
Macrophages are exploited from an innate wound healing response to facilitate cancer metastasis
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Author / Creator
Muliaditan, Tamara , Caron, Jonathan , Okesola, Mary , Opzoomer, James W. , Kosti, Paris , Georgouli, Mirella , Gordon, Peter , Lall, Sharanpreet , Kuzeva, Desislava M. , Pedro, Luisa , Shields, Jacqueline D. , Gillett, Cheryl E. , Diebold, Sandra S. , Sanz-Moreno, Victoria , Ng, Tony , Hoste, Esther and Arnold, James N.
Publisher
London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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Tumour-associated macrophages (TAMs) play an important role in tumour progression, which is facilitated by their ability to respond to environmental cues. Here we report, using murine models of breast cancer, that TAMs expressing fibroblast activation protein alpha (FAP) and haem oxygenase-1 (HO-1), which are also found in human breast cancer, repr...
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Macrophages are exploited from an innate wound healing response to facilitate cancer metastasis
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TN_cdi_doaj_primary_oai_doaj_org_article_8c66af37aaba412f826bf1e4aabd5fd7
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_8c66af37aaba412f826bf1e4aabd5fd7
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ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-018-05346-7