A phenotype-based forward genetic screen identifies Dnajb6 as a sick sinus syndrome gene
A phenotype-based forward genetic screen identifies Dnajb6 as a sick sinus syndrome gene
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Author / Creator
Ding, Yonghe , Lang, Di , Yan, Jianhua , Bu, Haisong , Li, Hongsong , Jiao, Kunli , Yang, Jingchun , Ni, Haibo , Morotti, Stefano , Le, Tai , Clark, Karl J , Port, Jenna , Ekker, Stephen C , Cao, Hung , Zhang, Yuji , Wang, Jun , Grandi, Eleonora , Li, Zhiqiang , Shi, Yongyong , Li, Yigang , Glukhov, Alexey V and Xu, Xiaolei
Publisher
England: eLife Sciences Publications Ltd
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English
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Publisher
England: eLife Sciences Publications Ltd
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Contents
Previously we showed the generation of a protein trap library made with the gene-break transposon (GBT) in zebrafish (
) that could be used to facilitate novel functional genome annotation towards understanding molecular underpinnings of human diseases (Ichino et al, 2020). Here, we report a significant application of this library for discoverin...
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Full title
A phenotype-based forward genetic screen identifies Dnajb6 as a sick sinus syndrome gene
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TN_cdi_doaj_primary_oai_doaj_org_article_8c6ea34b6857407bab43f1949ac3eec1
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_8c6ea34b6857407bab43f1949ac3eec1
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ISSN
2050-084X
E-ISSN
2050-084X
DOI
10.7554/eLife.77327
