The isocyanide SN2 reaction
The isocyanide SN2 reaction
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Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Scope and Contents
Contents
The S
N
2 nucleophilic substitution reaction is a vital organic transformation used for drug and natural product synthesis. Nucleophiles like cyanide, oxygen, nitrogen, sulfur, or phosphorous replace halogens or sulfonyl esters, forming new bonds. Isocyanides exhibit unique C-centered lone pair σ and π* orbitals, enabling diverse radical and...
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Full title
The isocyanide SN2 reaction
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TN_cdi_doaj_primary_oai_doaj_org_article_8c7c39542fac4d56b118ccd4bb6ab527
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_8c7c39542fac4d56b118ccd4bb6ab527
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ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-023-41253-2