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Heparan sulfates facilitate harmless amyloidogenic fibril formation interacting with elastin-like pe...

Heparan sulfates facilitate harmless amyloidogenic fibril formation interacting with elastin-like pe...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_8c820a60bdf24a928d8f6ac0b53ba66d

Heparan sulfates facilitate harmless amyloidogenic fibril formation interacting with elastin-like peptides

About this item

Full title

Heparan sulfates facilitate harmless amyloidogenic fibril formation interacting with elastin-like peptides

Publisher

London: Nature Publishing Group UK

Journal title

Scientific reports, 2018-02, Vol.8 (1), p.3115-11, Article 3115

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Heparan sulfates (HSs) modulate tissue elasticity in physiopathological conditions by interacting with various matrix constituents as tropoelastin and elastin-derived peptides. HSs bind also to protein moieties accelerating amyloid formation and influencing cytotoxic properties of insoluble fibrils. Interestingly, amyloidogenic polypeptides, despit...

Alternative Titles

Full title

Heparan sulfates facilitate harmless amyloidogenic fibril formation interacting with elastin-like peptides

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_8c820a60bdf24a928d8f6ac0b53ba66d

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_8c820a60bdf24a928d8f6ac0b53ba66d

Other Identifiers

ISSN

2045-2322

E-ISSN

2045-2322

DOI

10.1038/s41598-018-21472-0

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