Nuclear retention of unspliced HIV-1 RNA as a reversible post-transcriptional block in latency
Nuclear retention of unspliced HIV-1 RNA as a reversible post-transcriptional block in latency
About this item
Full title
Author / Creator
Dorman, Agnieszka , Bendoumou, Maryam , Valaitienė, Aurelija , Wadas, Jakub , Ali, Haider , Dutilleul, Antoine , Maiuri, Paolo , Nestola, Lorena , Bociaga-Jasik, Monika , Mchantaf, Gilbert , Necsoi, Coca , De Wit, Stéphane , Avettand-Fenoël, Véronique , Marcello, Alessandro , Pyrc, Krzysztof , Pasternak, Alexander O. , Van Lint, Carine and Kula-Pacurar, Anna
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
Formats
Publication information
Publisher
London: Nature Publishing Group UK
Subjects
More information
Scope and Contents
Contents
HIV-1 latency is mainly characterized at transcriptional level, and little is known about post-transcriptional mechanisms and their contribution to reactivation. The viral protein Rev controls the nucleocytoplasmic export of unspliced and singly-spliced RNA that is central to proviral replication-competence and is therefore a prerequisite for effic...
Alternative Titles
Full title
Nuclear retention of unspliced HIV-1 RNA as a reversible post-transcriptional block in latency
Authors, Artists and Contributors
Author / Creator
Bendoumou, Maryam
Valaitienė, Aurelija
Wadas, Jakub
Ali, Haider
Dutilleul, Antoine
Maiuri, Paolo
Nestola, Lorena
Bociaga-Jasik, Monika
Mchantaf, Gilbert
Necsoi, Coca
De Wit, Stéphane
Avettand-Fenoël, Véronique
Marcello, Alessandro
Pyrc, Krzysztof
Pasternak, Alexander O.
Van Lint, Carine
Kula-Pacurar, Anna
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_8c844a84de69432f90496f423a2b8dba
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_8c844a84de69432f90496f423a2b8dba
Other Identifiers
ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-025-57290-y
