Effects of Claudin-1 on the Action of Clostridium perfringens Enterotoxin in Caco-2 Cells
Effects of Claudin-1 on the Action of Clostridium perfringens Enterotoxin in Caco-2 Cells
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Publisher
Switzerland: MDPI AG
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Language
English
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Publisher
Switzerland: MDPI AG
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Contents
Clostridium perfringens enterotoxin (CPE) contributes to diarrhea and an often-lethal enterotoxemia. CPE action starts when it binds to claudin receptors, forming a small complex (90 kDa). Six small complexes then oligomerize to create prepores, followed by insertion of beta-hairpins from CPE to form beta-barrel pores named CH-1 or CH-2. Of the ~27...
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Full title
Effects of Claudin-1 on the Action of Clostridium perfringens Enterotoxin in Caco-2 Cells
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TN_cdi_doaj_primary_oai_doaj_org_article_8c9594d75b2f45c4817835e03e321bfe
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_8c9594d75b2f45c4817835e03e321bfe
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ISSN
2072-6651
E-ISSN
2072-6651
DOI
10.3390/toxins11100582
