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Gingival solitary chemosensory cells are immune sentinels for periodontitis

Gingival solitary chemosensory cells are immune sentinels for periodontitis

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_8caffc7909634deb85a1fda385dca1cc

Gingival solitary chemosensory cells are immune sentinels for periodontitis

About this item

Full title

Gingival solitary chemosensory cells are immune sentinels for periodontitis

Publisher

London: Nature Publishing Group UK

Journal title

Nature communications, 2019-10, Vol.10 (1), p.4496-11, Article 4496

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Solitary chemosensory cells (SCCs) are epithelial sentinels that utilize bitter Tas2r receptors and coupled taste transduction elements to detect pathogenic bacterial metabolites, triggering host defenses to control the infection. Here we report that SCCs are present in mouse gingival junctional epithelium, where they express several Tas2rs and the...

Alternative Titles

Full title

Gingival solitary chemosensory cells are immune sentinels for periodontitis

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_8caffc7909634deb85a1fda385dca1cc

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_8caffc7909634deb85a1fda385dca1cc

Other Identifiers

ISSN

2041-1723

E-ISSN

2041-1723

DOI

10.1038/s41467-019-12505-x

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