Carboplatin response in preclinical models for ovarian cancer: comparison of 2D monolayers, spheroid...
Carboplatin response in preclinical models for ovarian cancer: comparison of 2D monolayers, spheroids, ex vivo tumors and in vivo models
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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Epithelial ovarian cancer (EOC) is the most lethal gynecological cancer. Among the key challenges in developing effective therapeutics is the poor translation of preclinical models used in the drug discovery pipeline. This leaves drug attrition rates and costs at an unacceptably high level. Previous work has highlighted the discrepancies in therape...
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Carboplatin response in preclinical models for ovarian cancer: comparison of 2D monolayers, spheroids, ex vivo tumors and in vivo models
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TN_cdi_doaj_primary_oai_doaj_org_article_8cf5cb2dcdec424aabc6b0c6535c4a57
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_8cf5cb2dcdec424aabc6b0c6535c4a57
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ISSN
2045-2322
E-ISSN
2045-2322
DOI
10.1038/s41598-021-97434-w
