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Perturbed Wnt signaling leads to neuronal migration delay, altered interhemispheric connections and...

Perturbed Wnt signaling leads to neuronal migration delay, altered interhemispheric connections and...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_8d2f9638ad8e4f4bba3636fccca2602d

Perturbed Wnt signaling leads to neuronal migration delay, altered interhemispheric connections and impaired social behavior

About this item

Full title

Perturbed Wnt signaling leads to neuronal migration delay, altered interhemispheric connections and impaired social behavior

Publisher

London: Nature Publishing Group UK

Journal title

Nature communications, 2017-10, Vol.8 (1), p.1158-15, Article 1158

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Perturbed neuronal migration and circuit development have been implicated in the pathogenesis of neurodevelopmental diseases; however, the direct steps linking these developmental errors to behavior alterations remain unknown. Here we demonstrate that Wnt/C-Kit signaling is a key regulator of glia-guided radial migration in rat somatosensory cortex...

Alternative Titles

Full title

Perturbed Wnt signaling leads to neuronal migration delay, altered interhemispheric connections and impaired social behavior

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_8d2f9638ad8e4f4bba3636fccca2602d

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_8d2f9638ad8e4f4bba3636fccca2602d

Other Identifiers

ISSN

2041-1723

E-ISSN

2041-1723

DOI

10.1038/s41467-017-01046-w

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