Calcineurin inhibition enhances Caenorhabditis elegans lifespan by defecation defects-mediated calor...
Calcineurin inhibition enhances Caenorhabditis elegans lifespan by defecation defects-mediated calorie restriction and nuclear hormone signaling
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England: eLife Sciences Publications Ltd
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English
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England: eLife Sciences Publications Ltd
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Calcineurin is a highly conserved calcium/calmodulin-dependent serine/threonine protein phosphatase with diverse functions. Inhibition of calcineurin is known to enhance the lifespan of
through multiple signaling pathways. Aiming to study the role of calcineurin in regulating innate immunity, we discover that calcineurin is required for the rhyt...
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Calcineurin inhibition enhances Caenorhabditis elegans lifespan by defecation defects-mediated calorie restriction and nuclear hormone signaling
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TN_cdi_doaj_primary_oai_doaj_org_article_8d5a470e86f4478f91dd1f3cf87c1b46
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_8d5a470e86f4478f91dd1f3cf87c1b46
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ISSN
2050-084X
E-ISSN
2050-084X
DOI
10.7554/eLife.89572
