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Protease-activated receptor 1 in the pathogenesis of cystic fibrosis

Protease-activated receptor 1 in the pathogenesis of cystic fibrosis

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_8d8088cffcb644dfb46d18e31d1a00c3

Protease-activated receptor 1 in the pathogenesis of cystic fibrosis

About this item

Full title

Protease-activated receptor 1 in the pathogenesis of cystic fibrosis

Publisher

England: British Thoracic Society

Journal title

BMJ open respiratory research, 2025-01, Vol.12 (1), p.e002960

Language

English

Formats

Publication information

Publisher

England: British Thoracic Society

More information

Scope and Contents

Contents

BackgroundThe most common cause of death in those with cystic fibrosis (CF) is respiratory failure due to bronchiectasis resulting from repeated cycles of respiratory infection and inflammation. Protease-activated receptor 1 (PAR1) is a cell surface receptor activated by serine proteases including neutrophil elastase, which is recognised as a poten...

Alternative Titles

Full title

Protease-activated receptor 1 in the pathogenesis of cystic fibrosis

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_8d8088cffcb644dfb46d18e31d1a00c3

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_8d8088cffcb644dfb46d18e31d1a00c3

Other Identifiers

ISSN

2052-4439

E-ISSN

2052-4439

DOI

10.1136/bmjresp-2024-002960

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