Obesity dysregulates the pulmonary antiviral immune response
Obesity dysregulates the pulmonary antiviral immune response
About this item
Full title
Author / Creator
Almond, Mark , Farne, Hugo A. , Jackson, Millie M. , Jha, Akhilesh , Katsoulis, Orestis , Pitts, Oliver , Tunstall, Tanushree , Regis, Eteri , Dunning, Jake , Byrne, Adam J. , Mallia, Patrick , Kon, Onn Min , Saunders, Ken A. , Simpson, Karen D. , Snelgrove, Robert J. , Openshaw, Peter J. M. , Edwards, Michael R. , Barclay, Wendy S. , Heaney, Liam M. , Johnston, Sebastian L. and Singanayagam, Aran
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
Formats
Publication information
Publisher
London: Nature Publishing Group UK
Subjects
More information
Scope and Contents
Contents
Obesity is a well-recognized risk factor for severe influenza infections but the mechanisms underlying susceptibility are poorly understood. Here, we identify that obese individuals have deficient pulmonary antiviral immune responses in bronchoalveolar lavage cells but not in bronchial epithelial cells or peripheral blood dendritic cells. We show t...
Alternative Titles
Full title
Obesity dysregulates the pulmonary antiviral immune response
Authors, Artists and Contributors
Author / Creator
Farne, Hugo A.
Jackson, Millie M.
Jha, Akhilesh
Katsoulis, Orestis
Pitts, Oliver
Tunstall, Tanushree
Regis, Eteri
Dunning, Jake
Byrne, Adam J.
Mallia, Patrick
Kon, Onn Min
Saunders, Ken A.
Simpson, Karen D.
Snelgrove, Robert J.
Openshaw, Peter J. M.
Edwards, Michael R.
Barclay, Wendy S.
Heaney, Liam M.
Johnston, Sebastian L.
Singanayagam, Aran
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_8d985523dc6242578a25e3fd4216932b
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_8d985523dc6242578a25e3fd4216932b
Other Identifiers
ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-023-42432-x
