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Natural immunity to malaria preferentially targets the endothelial protein C receptor-binding region...

Natural immunity to malaria preferentially targets the endothelial protein C receptor-binding region...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_8dcbf8acf8964b7893f4a4ecb78030a5

Natural immunity to malaria preferentially targets the endothelial protein C receptor-binding regions of PfEMP1s

About this item

Full title

Natural immunity to malaria preferentially targets the endothelial protein C receptor-binding regions of PfEMP1s

Publisher

United States: American Society for Microbiology

Journal title

mSphere, 2023-10, Vol.8 (5), p.e0045123-e0045123

Language

English

Formats

Publication information

Publisher

United States: American Society for Microbiology

More information

Scope and Contents

Contents

Antibody responses to variant surface antigens (VSAs) produced by the malaria parasite
Plasmodium falciparum
may contribute to age-related natural immunity to severe malaria. One VSA family,
P. falciparum
erythrocyte membrane protein-1 (PfEMP1), includes a subset of proteins that binds endothelial protein C receptor (EPCR) in human host...

Alternative Titles

Full title

Natural immunity to malaria preferentially targets the endothelial protein C receptor-binding regions of PfEMP1s

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_8dcbf8acf8964b7893f4a4ecb78030a5

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_8dcbf8acf8964b7893f4a4ecb78030a5

Other Identifiers

ISSN

2379-5042

E-ISSN

2379-5042

DOI

10.1128/msphere.00451-23

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