Dengue virus modulates critical cell cycle regulatory proteins in human megakaryocyte cells
Dengue virus modulates critical cell cycle regulatory proteins in human megakaryocyte cells
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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Suppression of human megakaryocytes by dengue virus (DENV) infection significantly reduces the platelet count that eventually leads to thrombocytopenia, severe dengue and death. To understand DENV interactions with megakaryocytes, we investigated the cell cycle in leukemic human megakaryocytic in vitro cell line (MEG-01 cells). Megakaryocytes are k...
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Dengue virus modulates critical cell cycle regulatory proteins in human megakaryocyte cells
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TN_cdi_doaj_primary_oai_doaj_org_article_8e28e4c86140481fbea3ae36e6a1446b
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_8e28e4c86140481fbea3ae36e6a1446b
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ISSN
2045-2322
E-ISSN
2045-2322
DOI
10.1038/s41598-025-02640-5
