CXCR6 is required for antitumor efficacy of intratumoral CD8+ T cell
CXCR6 is required for antitumor efficacy of intratumoral CD8+ T cell
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Author / Creator
Wang, Binglin , Wang, Yi , Sun, Xiaofan , Deng, Guoliang , Huang, Wei , Wu, Xingxin , Gu, Yanghong , Tian, Zhigang , Fan, Zhimin , Xu, Qiang , Chen, Hongqi and Sun, Yang
Publisher
England: BMJ Publishing Group LTD
Journal title
Language
English
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Publisher
England: BMJ Publishing Group LTD
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Contents
BackgroundIncreasing infiltration of CD8+ T cells within tumor tissue predicts a better prognosis and is essential for response to checkpoint blocking therapy. Furthermore, current clinical protocols use unfractioned T cell populations as the starting point for transduction of chimeric antigen receptors (CARs)-modified T cells, but the optimal T ce...
Alternative Titles
Full title
CXCR6 is required for antitumor efficacy of intratumoral CD8+ T cell
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Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_8e475ffef11c4ac19294e49e7949452a
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_8e475ffef11c4ac19294e49e7949452a
Other Identifiers
ISSN
2051-1426
E-ISSN
2051-1426
DOI
10.1136/jitc-2021-003100
