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Ablation of VLA4 in multiple myeloma cells redirects tumor spread and prolongs survival

Ablation of VLA4 in multiple myeloma cells redirects tumor spread and prolongs survival

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_8e51a8a6e17d4addb9f29bbbabe3d928

Ablation of VLA4 in multiple myeloma cells redirects tumor spread and prolongs survival

About this item

Full title

Ablation of VLA4 in multiple myeloma cells redirects tumor spread and prolongs survival

Publisher

London: Nature Publishing Group UK

Journal title

Scientific reports, 2022-01, Vol.12 (1), p.30-30, Article 30

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Multiple myeloma (MM) is a cancer of bone marrow (BM) plasma cells, which is increasingly treatable but still incurable. In 90% of MM patients, severe osteolysis results from pathological interactions between MM cells and the bone microenvironment. Delineating specific molecules and pathways for their role in cancer supportive interactions in the B...

Alternative Titles

Full title

Ablation of VLA4 in multiple myeloma cells redirects tumor spread and prolongs survival

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_8e51a8a6e17d4addb9f29bbbabe3d928

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_8e51a8a6e17d4addb9f29bbbabe3d928

Other Identifiers

ISSN

2045-2322

E-ISSN

2045-2322

DOI

10.1038/s41598-021-03748-0

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