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WNT5a-ROR Signaling Is Essential for Alveologenesis

WNT5a-ROR Signaling Is Essential for Alveologenesis

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_8e952bc39d684b2baefe8fe97f7f247d

WNT5a-ROR Signaling Is Essential for Alveologenesis

About this item

Full title

WNT5a-ROR Signaling Is Essential for Alveologenesis

Publisher

Switzerland: MDPI

Journal title

Cells (Basel, Switzerland), 2020-02, Vol.9 (2), p.384

Language

English

Formats

Publication information

Publisher

Switzerland: MDPI

More information

Scope and Contents

Contents

WNT5a is a mainly "non-canonical" WNT ligand whose dysregulation is observed in lung diseases such as idiopathic pulmonary fibrosis (IPF), chronic obstructive pulmonary disease (COPD) and asthma. Germline deletion of Wnt5a disrupts embryonic lung development. However, the temporal-specific function of WNT5a remains unknown. In this study, we genera...

Alternative Titles

Full title

WNT5a-ROR Signaling Is Essential for Alveologenesis

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_8e952bc39d684b2baefe8fe97f7f247d

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_8e952bc39d684b2baefe8fe97f7f247d

Other Identifiers

ISSN

2073-4409

E-ISSN

2073-4409

DOI

10.3390/cells9020384

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