Tsc1-mTORC1 signaling controls striatal dopamine release and cognitive flexibility
Tsc1-mTORC1 signaling controls striatal dopamine release and cognitive flexibility
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London: Nature Publishing Group UK
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Language
English
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London: Nature Publishing Group UK
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Contents
Tuberous Sclerosis Complex (TSC) is a neurodevelopmental disorder caused by mutations in
TSC1
or
TSC2
, which encode proteins that negatively regulate mTOR complex 1 (mTORC1). TSC is associated with significant cognitive, psychiatric, and behavioral problems, collectively termed TSC-Associated Neuropsychiatric Disorders (TAND), and the...
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Tsc1-mTORC1 signaling controls striatal dopamine release and cognitive flexibility
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TN_cdi_doaj_primary_oai_doaj_org_article_8f206497b65e4d93a92d89d476e37c28
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_8f206497b65e4d93a92d89d476e37c28
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ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-019-13396-8
