Use of cilomilast-loaded phosphatiosomes to suppress neutrophilic inflammation for attenuating acute...
Use of cilomilast-loaded phosphatiosomes to suppress neutrophilic inflammation for attenuating acute lung injury: the effect of nanovesicular surface charge
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England: BioMed Central Ltd
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English
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England: BioMed Central Ltd
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Cilomilast is a phosphodiesterase 4 (PDE4) inhibitor for treating inflammatory lung diseases. This agent has a narrow therapeutic index with significant adverse effects on the nervous system. This study was conducted to entrap cilomilast into PEGylated phosphatidylcholine-rich niosomes (phosphatiosomes) to improve pulmonary delivery via the strong...
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Use of cilomilast-loaded phosphatiosomes to suppress neutrophilic inflammation for attenuating acute lung injury: the effect of nanovesicular surface charge
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TN_cdi_doaj_primary_oai_doaj_org_article_8f20de41df2b4df78620f32caece9311
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_8f20de41df2b4df78620f32caece9311
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ISSN
1477-3155
E-ISSN
1477-3155
DOI
10.1186/s12951-018-0364-z