MiR-199a-modified exosomes from adipose tissue-derived mesenchymal stem cells improve hepatocellular...
MiR-199a-modified exosomes from adipose tissue-derived mesenchymal stem cells improve hepatocellular carcinoma chemosensitivity through mTOR pathway
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Author / Creator
Lou, Guohua , Chen, Liang , Xia, Caixia , Wang, Weina , Qi, Jinjin , Li, Aichun , Zhao, Liying , Chen, Zhi , Zheng, Min and Liu, Yanning
Publisher
England: BioMed Central Ltd
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Language
English
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Publisher
England: BioMed Central Ltd
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Contents
MiR-199a-3p (miR-199a) can enhance the chemosensitivity of hepatocellular carcinoma (HCC). Because of the easy degradation of miRNA by direct infusion, effective vehicle-mediated delivery of miR-199a may represent a new strategy for improving HCC chemotherapy. Considering mesenchymal stem cell (MSC)-derived exosomes as promising natural nanovectors...
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Full title
MiR-199a-modified exosomes from adipose tissue-derived mesenchymal stem cells improve hepatocellular carcinoma chemosensitivity through mTOR pathway
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TN_cdi_doaj_primary_oai_doaj_org_article_8f402367dbf744b5b9b00d184958e212
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_8f402367dbf744b5b9b00d184958e212
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ISSN
1756-9966,0392-9078
E-ISSN
1756-9966
DOI
10.1186/s13046-019-1512-5