ATM phosphorylation of the actin-binding protein drebrin controls oxidation stress-resistance in mam...
ATM phosphorylation of the actin-binding protein drebrin controls oxidation stress-resistance in mammalian neurons and C. elegans
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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Drebrin (DBN) regulates cytoskeletal functions during neuronal development, and is thought to contribute to structural and functional synaptic changes associated with aging and Alzheimer’s disease. Here we show that DBN coordinates stress signalling with cytoskeletal dynamics, via a mechanism involving kinase ataxia-telangiectasia mutated (ATM). An...
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ATM phosphorylation of the actin-binding protein drebrin controls oxidation stress-resistance in mammalian neurons and C. elegans
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TN_cdi_doaj_primary_oai_doaj_org_article_8f4a9676b36d4e899073e6805e0d669d
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_8f4a9676b36d4e899073e6805e0d669d
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2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-019-08420-w
