Contribution of protein Gar1 to the RNA-guided and RNA-independent rRNA:Ψ-synthase activities of the...
Contribution of protein Gar1 to the RNA-guided and RNA-independent rRNA:Ψ-synthase activities of the archaeal Cbf5 protein
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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Contents
Archaeal RNA:pseudouridine-synthase (PUS) Cbf5 in complex with proteins L7Ae, Nop10 and Gar1, and guide box H/ACA sRNAs forms ribonucleoprotein (RNP) catalysts that insure the conversion of uridines into pseudouridines (Ψs) in ribosomal RNAs (rRNAs). Nonetheless, in the absence of guide RNA, Cbf5 catalyzes the
in vitro
formation of Ψ
2603<...
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Full title
Contribution of protein Gar1 to the RNA-guided and RNA-independent rRNA:Ψ-synthase activities of the archaeal Cbf5 protein
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TN_cdi_doaj_primary_oai_doaj_org_article_8f4e286c4b614fb4bbbba9971d936c88
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_8f4e286c4b614fb4bbbba9971d936c88
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ISSN
2045-2322
E-ISSN
2045-2322
DOI
10.1038/s41598-018-32164-0
