Frequent epigenetic inactivation of RASSF2 in thyroid cancer and functional consequences
Frequent epigenetic inactivation of RASSF2 in thyroid cancer and functional consequences
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England: BioMed Central Ltd
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Language
English
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England: BioMed Central Ltd
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The Ras association domain family (RASSF) encodes for distinct tumor suppressors and several members are frequently silenced in human cancer. In our study, we analyzed the role of RASSF2, RASSF3, RASSF4, RASSF5A, RASSF5C and RASSF6 and the effectors MST1, MST2 and WW45 in thyroid carcinogenesis.
Frequent methylation of the RASSF2 and RASSF5A CpG...
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Full title
Frequent epigenetic inactivation of RASSF2 in thyroid cancer and functional consequences
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TN_cdi_doaj_primary_oai_doaj_org_article_8f5e5152de804ccaae1736afe16dc2f6
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_8f5e5152de804ccaae1736afe16dc2f6
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ISSN
1476-4598
E-ISSN
1476-4598
DOI
10.1186/1476-4598-9-264
