Autoimmune activation of the GnRH receptor induces insulin resistance independent of obesity in a fe...
Autoimmune activation of the GnRH receptor induces insulin resistance independent of obesity in a female rat model
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United States: John Wiley & Sons, Inc
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English
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United States: John Wiley & Sons, Inc
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Polycystic ovary syndrome (PCOS), a metabolic and reproductive disease, is frequently associated with type 2 diabetes. We have demonstrated activating autoantibodies (AAb) directed toward the second extracellular loop (ECL2) of the gonadotropin‐releasing hormone receptor (GnRHR) are present in a significant subgroup of PCOS patients. It is unclear...
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Autoimmune activation of the GnRH receptor induces insulin resistance independent of obesity in a female rat model
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TN_cdi_doaj_primary_oai_doaj_org_article_8f6cae1aa000431a9f560a0dfdd209ce
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_8f6cae1aa000431a9f560a0dfdd209ce
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E-ISSN
2051-817X
DOI
10.14814/phy2.14672