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Autoimmune activation of the GnRH receptor induces insulin resistance independent of obesity in a fe...

Autoimmune activation of the GnRH receptor induces insulin resistance independent of obesity in a fe...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_8f6cae1aa000431a9f560a0dfdd209ce

Autoimmune activation of the GnRH receptor induces insulin resistance independent of obesity in a female rat model

About this item

Full title

Autoimmune activation of the GnRH receptor induces insulin resistance independent of obesity in a female rat model

Publisher

United States: John Wiley & Sons, Inc

Journal title

Physiological reports, 2021-01, Vol.8 (24), p.e14672-n/a

Language

English

Formats

Publication information

Publisher

United States: John Wiley & Sons, Inc

More information

Scope and Contents

Contents

Polycystic ovary syndrome (PCOS), a metabolic and reproductive disease, is frequently associated with type 2 diabetes. We have demonstrated activating autoantibodies (AAb) directed toward the second extracellular loop (ECL2) of the gonadotropin‐releasing hormone receptor (GnRHR) are present in a significant subgroup of PCOS patients. It is unclear...

Alternative Titles

Full title

Autoimmune activation of the GnRH receptor induces insulin resistance independent of obesity in a female rat model

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_8f6cae1aa000431a9f560a0dfdd209ce

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_8f6cae1aa000431a9f560a0dfdd209ce

Other Identifiers

E-ISSN

2051-817X

DOI

10.14814/phy2.14672

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