Cellular hierarchy insights reveal leukemic stem-like cells and early death risk in acute promyelocy...
Cellular hierarchy insights reveal leukemic stem-like cells and early death risk in acute promyelocytic leukemia
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Author / Creator
Jin, Wen , Dai, Yuting , Chen, Li , Zhu, Honghu , Dong, Fangyi , Zhu, Hongming , Meng, Guoyu , Li, Junmin , Chen, Saijuan , Chen, Zhu , Fang, Hai and Wang, Kankan
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
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Publication information
Publisher
London: Nature Publishing Group UK
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Contents
Acute promyelocytic leukemia (APL) represents a paradigm for targeted differentiation therapy, with a minority of patients experiencing treatment failure and even early death. We here report a comprehensive single-cell analysis of 16 APL patients, uncovering cellular compositions and their impact on all-trans retinoic acid (ATRA) response in vivo a...
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Full title
Cellular hierarchy insights reveal leukemic stem-like cells and early death risk in acute promyelocytic leukemia
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Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_8faf8f577f5841a1af926a0e17e57d1f
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_8faf8f577f5841a1af926a0e17e57d1f
Other Identifiers
ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-024-45737-7
