Whole-Body Distribution of Donepezil as an Acetylcholinesterase Inhibitor after Oral Administration...
Whole-Body Distribution of Donepezil as an Acetylcholinesterase Inhibitor after Oral Administration in Normal Human Subjects: A 11C-donepezil PET Study
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Mashhad: Asia Oceania Journal of Nuclear Medicine & Biology
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Mashhad: Asia Oceania Journal of Nuclear Medicine & Biology
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Objective(s):It is difficult to investigate the whole-body distribution of an orally administered drug by means of positron emission tomography (PET), owing to the short physical half-life of radionuclides, especially when 11C-labeled compounds are tested. Therefore, we aimed to examine the whole-body distribution of donepezil (DNP) as an acetylcho...
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Whole-Body Distribution of Donepezil as an Acetylcholinesterase Inhibitor after Oral Administration in Normal Human Subjects: A 11C-donepezil PET Study
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TN_cdi_doaj_primary_oai_doaj_org_article_8fdc77f1ffc647078ab27025ca0772a8
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_8fdc77f1ffc647078ab27025ca0772a8
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2322-5718
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2322-5726
DOI
10.22038/aojnmb.2016.7513
