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The APMAP interactome reveals new modulators of APP processing and beta-amyloid production that are...

The APMAP interactome reveals new modulators of APP processing and beta-amyloid production that are...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_8fe056cdaf0b4eb9b26c8f136da778f5

The APMAP interactome reveals new modulators of APP processing and beta-amyloid production that are altered in Alzheimer's disease

About this item

Full title

The APMAP interactome reveals new modulators of APP processing and beta-amyloid production that are altered in Alzheimer's disease

Publisher

England: BioMed Central Ltd

Journal title

Acta neuropathologica communications, 2019-01, Vol.7 (1), p.13-13, Article 13

Language

English

Formats

Publication information

Publisher

England: BioMed Central Ltd

More information

Scope and Contents

Contents

The adipocyte plasma membrane-associated protein APMAP is expressed in the brain where it associates with γ-secretase, a protease responsible for the generation of the amyloid-β peptides (Aβ) implicated in the pathogenesis of Alzheimer's disease (AD). In this study, behavioral investigations revealed spatial learning and memory deficiencies in our...

Alternative Titles

Full title

The APMAP interactome reveals new modulators of APP processing and beta-amyloid production that are altered in Alzheimer's disease

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_8fe056cdaf0b4eb9b26c8f136da778f5

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_8fe056cdaf0b4eb9b26c8f136da778f5

Other Identifiers

ISSN

2051-5960

E-ISSN

2051-5960

DOI

10.1186/s40478-019-0660-3

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