PI(18:1/18:1) is a SCD1-derived lipokine that limits stress signaling
PI(18:1/18:1) is a SCD1-derived lipokine that limits stress signaling
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Author / Creator
Thürmer, Maria , Gollowitzer, André , Pein, Helmut , Neukirch, Konstantin , Gelmez, Elif , Waltl, Lorenz , Wielsch, Natalie , Winkler, René , Löser, Konstantin , Grander, Julia , Hotze, Madlen , Harder, Sönke , Döding, Annika , Meßner, Martina , Troisi, Fabiana , Ardelt, Maximilian , Schlüter, Hartmut , Pachmayr, Johanna , Gutiérrez-Gutiérrez, Óscar , Rudolph, Karl Lenhard , Thedieck, Kathrin , Schulze-Späte, Ulrike , González-Estévez, Cristina , Kosan, Christian , Svatoš, Aleš , Kwiatkowski, Marcel and Koeberle, Andreas
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
Formats
Publication information
Publisher
London: Nature Publishing Group UK
Subjects
More information
Scope and Contents
Contents
Cytotoxic stress activates stress-activated kinases, initiates adaptive mechanisms, including the unfolded protein response (UPR) and autophagy, and induces programmed cell death. Fatty acid unsaturation, controlled by stearoyl-CoA desaturase (SCD)1, prevents cytotoxic stress but the mechanisms are diffuse. Here, we show that 1,2-dioleoyl-
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Alternative Titles
Full title
PI(18:1/18:1) is a SCD1-derived lipokine that limits stress signaling
Authors, Artists and Contributors
Author / Creator
Gollowitzer, André
Pein, Helmut
Neukirch, Konstantin
Gelmez, Elif
Waltl, Lorenz
Wielsch, Natalie
Winkler, René
Löser, Konstantin
Grander, Julia
Hotze, Madlen
Harder, Sönke
Döding, Annika
Meßner, Martina
Troisi, Fabiana
Ardelt, Maximilian
Schlüter, Hartmut
Pachmayr, Johanna
Gutiérrez-Gutiérrez, Óscar
Rudolph, Karl Lenhard
Thedieck, Kathrin
Schulze-Späte, Ulrike
González-Estévez, Cristina
Kosan, Christian
Svatoš, Aleš
Kwiatkowski, Marcel
Koeberle, Andreas
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_8fff1ccb32314909871bbf27bc179a32
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_8fff1ccb32314909871bbf27bc179a32
Other Identifiers
ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-022-30374-9
