Binding Zinc and Oxo-Vanadium Insulin-Mimetic Complexes to Phosphatase Enzymes: Structure, Electroni...
Binding Zinc and Oxo-Vanadium Insulin-Mimetic Complexes to Phosphatase Enzymes: Structure, Electronics and Implications
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Basel: MDPI AG
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English
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Basel: MDPI AG
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We explore the structural and electronic properties of representative insulin-mimetic oxovanadium and zinc complexes as computed in vacuum, in water clusters and upon binding to PTEN and PTP1B phosphatases. Albeit diverse, the enzymes’ active sites represent evolutionary variant choices of the same type of biochemistry. Though different in respect...
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Binding Zinc and Oxo-Vanadium Insulin-Mimetic Complexes to Phosphatase Enzymes: Structure, Electronics and Implications
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TN_cdi_doaj_primary_oai_doaj_org_article_8fffda7a76fe4d4492d48e330d8aa108
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_8fffda7a76fe4d4492d48e330d8aa108
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ISSN
1420-3049
E-ISSN
1420-3049
DOI
10.3390/molecules30071469
