Validation of computational determination of microsatellite status using whole exome sequencing data...
Validation of computational determination of microsatellite status using whole exome sequencing data from colorectal cancer patients
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Publisher
England: BioMed Central Ltd
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Language
English
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Publisher
England: BioMed Central Ltd
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Microsatellite instability (MSI), resulting from a defective mismatch repair system, occurs in approximately 15% of sporadic colorectal cancers (CRC). Since MSI is associated with a poor response to 5-fluorouracile based chemotherapy and is a positive predictive marker of immunotherapy, it is routine practice to evaluate the MSI status of resected...
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Validation of computational determination of microsatellite status using whole exome sequencing data from colorectal cancer patients
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TN_cdi_doaj_primary_oai_doaj_org_article_90060eda57db48bc8f45e239d40eccb9
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_90060eda57db48bc8f45e239d40eccb9
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ISSN
1471-2407
E-ISSN
1471-2407
DOI
10.1186/s12885-019-6227-7
