Castration delays epigenetic aging and feminizes DNA methylation at androgen-regulated loci
Castration delays epigenetic aging and feminizes DNA methylation at androgen-regulated loci
About this item
Full title
Author / Creator
Sugrue, Victoria J , Zoller, Joseph Alan , Narayan, Pritika , Lu, Ake T , Ortega-Recalde, Oscar J , Grant, Matthew J , Bawden, C Simon , Rudiger, Skye R , Haghani, Amin , Bond, Donna M , Hore, Reuben R , Garratt, Michael , Sears, Karen E , Wang, Nan , Yang, Xiangdong William , Snell, Russell G , Hore, Timothy A and Horvath, Steve
Publisher
Cambridge: eLife Science Publications, Ltd
Journal title
Language
English
Formats
Publication information
Publisher
Cambridge: eLife Science Publications, Ltd
Subjects
More information
Scope and Contents
Contents
In mammals, females generally live longer than males. Nevertheless, the mechanisms underpinning sex-dependent longevity are currently unclear. Epigenetic clocks are powerful biological biomarkers capable of precisely estimating chronological age and identifying novel factors influencing the aging rate using only DNA methylation data. In this study,...
Alternative Titles
Full title
Castration delays epigenetic aging and feminizes DNA methylation at androgen-regulated loci
Authors, Artists and Contributors
Author / Creator
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_901ed9d95cff4307a781c381e14cdfb3
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_901ed9d95cff4307a781c381e14cdfb3
Other Identifiers
ISSN
2050-084X
E-ISSN
2050-084X
DOI
10.7554/eLife.64932
