Streptococcus pyogenes pharyngitis elicits diverse antibody responses to key vaccine antigens influe...
Streptococcus pyogenes pharyngitis elicits diverse antibody responses to key vaccine antigens influenced by the imprint of past infections
About this item
Full title
Author / Creator
Osowicki, Joshua , Frost, Hannah R. , Azzopardi, Kristy I. , Whitcombe, Alana L. , McGregor, Reuben , Carlton, Lauren H. , Baker, Ciara , Fabri, Loraine , Pandey, Manisha , Good, Michael F. , Carapetis, Jonathan R. , Walker, Mark J. , Smeesters, Pierre R. , Licciardi, Paul V. , Moreland, Nicole J. , Hill, Danika L. and Steer, Andrew C.
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
Formats
Publication information
Publisher
London: Nature Publishing Group UK
Subjects
More information
Scope and Contents
Contents
Knowledge gaps regarding human immunity to
Streptococcus pyogenes
have impeded vaccine development. To address these gaps and evaluate vaccine candidates, we established a human challenge model of
S. pyogenes
pharyngitis. Here, we analyse antibody responses in serum and saliva against 19 antigens to identify characteristics distinguishi...
Alternative Titles
Full title
Streptococcus pyogenes pharyngitis elicits diverse antibody responses to key vaccine antigens influenced by the imprint of past infections
Authors, Artists and Contributors
Author / Creator
Frost, Hannah R.
Azzopardi, Kristy I.
Whitcombe, Alana L.
McGregor, Reuben
Carlton, Lauren H.
Baker, Ciara
Fabri, Loraine
Pandey, Manisha
Good, Michael F.
Carapetis, Jonathan R.
Walker, Mark J.
Smeesters, Pierre R.
Licciardi, Paul V.
Moreland, Nicole J.
Hill, Danika L.
Steer, Andrew C.
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_902639a54f2840948bfbd5b7db4041c1
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_902639a54f2840948bfbd5b7db4041c1
Other Identifiers
ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-024-54665-5