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Streptococcus pyogenes pharyngitis elicits diverse antibody responses to key vaccine antigens influe...

Streptococcus pyogenes pharyngitis elicits diverse antibody responses to key vaccine antigens influe...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_902639a54f2840948bfbd5b7db4041c1

Streptococcus pyogenes pharyngitis elicits diverse antibody responses to key vaccine antigens influenced by the imprint of past infections

About this item

Full title

Streptococcus pyogenes pharyngitis elicits diverse antibody responses to key vaccine antigens influenced by the imprint of past infections

Publisher

London: Nature Publishing Group UK

Journal title

Nature communications, 2024-12, Vol.15 (1), p.10506-14, Article 10506

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Knowledge gaps regarding human immunity to
Streptococcus pyogenes
have impeded vaccine development. To address these gaps and evaluate vaccine candidates, we established a human challenge model of
S. pyogenes
pharyngitis. Here, we analyse antibody responses in serum and saliva against 19 antigens to identify characteristics distinguishi...

Alternative Titles

Full title

Streptococcus pyogenes pharyngitis elicits diverse antibody responses to key vaccine antigens influenced by the imprint of past infections

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_902639a54f2840948bfbd5b7db4041c1

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_902639a54f2840948bfbd5b7db4041c1

Other Identifiers

ISSN

2041-1723

E-ISSN

2041-1723

DOI

10.1038/s41467-024-54665-5

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