Plasmepsin II–III copy number accounts for bimodal piperaquine resistance among Cambodian Plasmodium...
Plasmepsin II–III copy number accounts for bimodal piperaquine resistance among Cambodian Plasmodium falciparum
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Author / Creator
Bopp, Selina , Magistrado, Pamela , Wong, Wesley , Schaffner, Stephen F. , Mukherjee, Angana , Lim, Pharath , Dhorda, Mehul , Amaratunga, Chanaki , Woodrow, Charles J. , Ashley, Elizabeth A. , White, Nicholas J. , Dondorp, Arjen M. , Fairhurst, Rick M. , Ariey, Frederic , Menard, Didier , Wirth, Dyann F. and Volkman, Sarah K.
Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Contents
Multidrug resistant
Plasmodium falciparum
in Southeast Asia endangers regional malaria elimination and threatens to spread to other malaria endemic areas. Understanding mechanisms of piperaquine (PPQ) resistance is crucial for tracking its emergence and spread, and to develop effective strategies for overcoming it. Here we analyze a mechanism...
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Full title
Plasmepsin II–III copy number accounts for bimodal piperaquine resistance among Cambodian Plasmodium falciparum
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TN_cdi_doaj_primary_oai_doaj_org_article_9034c4b32e45414b8abd12e3feb18d67
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_9034c4b32e45414b8abd12e3feb18d67
Other Identifiers
ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-018-04104-z
