Large scale phenotype imputation and in vivo functional validation implicate ADAMTS14 as an adiposit...
Large scale phenotype imputation and in vivo functional validation implicate ADAMTS14 as an adiposity gene
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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Obesity remains an unmet global health burden. Detrimental anatomical distribution of body fat is a major driver of obesity-mediated mortality risk and is demonstrably heritable. However, our understanding of the full genetic contribution to human adiposity is incomplete, as few studies measure adiposity directly. To address this, we impute whole-b...
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Large scale phenotype imputation and in vivo functional validation implicate ADAMTS14 as an adiposity gene
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TN_cdi_doaj_primary_oai_doaj_org_article_903568c5d1ae45e28b5b075edb1b116a
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_903568c5d1ae45e28b5b075edb1b116a
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2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-022-35563-0