Genomic and oncogenic preference of HBV integration in hepatocellular carcinoma
Genomic and oncogenic preference of HBV integration in hepatocellular carcinoma
About this item
Full title
Author / Creator
Zhao, Ling-Hao , Liu, Xiao , Yan, He-Xin , Li, Wei-Yang , Zeng, Xi , Yang, Yuan , Zhao, Jie , Liu, Shi-Ping , Zhuang, Xue-Han , Lin, Chuan , Qin, Chen-Jie , Zhao, Yi , Pan, Ze-Ya , Huang, Gang , Liu, Hui , Zhang, Jin , Wang, Ruo-Yu , Yang, Yun , Wen, Wen , Lv, Gui-Shuai , Zhang, Hui-Lu , Wu, Han , Huang, Shuai , Wang, Ming-Da , Tang, Liang , Cao, Hong-Zhi , Wang, Ling , Lee, Tin-Lap , Jiang, Hui , Tan, Ye-Xiong , Yuan, Sheng-Xian , Hou, Guo-Jun , Tao, Qi-Fei , Xu, Qin-Guo , Zhang, Xiu-Qing , Wu, Meng-Chao , Xu, Xun , Wang, Jun , Yang, Huan-Ming , Zhou, Wei-Ping and Wang, Hong-Yang
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
Formats
Publication information
Publisher
London: Nature Publishing Group UK
Subjects
More information
Scope and Contents
Contents
Hepatitis B virus (HBV) can integrate into the human genome, contributing to genomic instability and hepatocarcinogenesis. Here by conducting high-throughput viral integration detection and RNA sequencing, we identify 4,225 HBV integration events in tumour and adjacent non-tumour samples from 426 patients with HCC. We show that HBV is prone to inte...
Alternative Titles
Full title
Genomic and oncogenic preference of HBV integration in hepatocellular carcinoma
Authors, Artists and Contributors
Author / Creator
Liu, Xiao
Yan, He-Xin
Li, Wei-Yang
Zeng, Xi
Yang, Yuan
Zhao, Jie
Liu, Shi-Ping
Zhuang, Xue-Han
Lin, Chuan
Qin, Chen-Jie
Zhao, Yi
Pan, Ze-Ya
Huang, Gang
Liu, Hui
Zhang, Jin
Wang, Ruo-Yu
Yang, Yun
Wen, Wen
Lv, Gui-Shuai
Zhang, Hui-Lu
Wu, Han
Huang, Shuai
Wang, Ming-Da
Tang, Liang
Cao, Hong-Zhi
Wang, Ling
Lee, Tin-Lap
Jiang, Hui
Tan, Ye-Xiong
Yuan, Sheng-Xian
Hou, Guo-Jun
Tao, Qi-Fei
Xu, Qin-Guo
Zhang, Xiu-Qing
Wu, Meng-Chao
Xu, Xun
Wang, Jun
Yang, Huan-Ming
Zhou, Wei-Ping
Wang, Hong-Yang
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_9037ae5413474dd6bc6a7cc68bd5d357
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_9037ae5413474dd6bc6a7cc68bd5d357
Other Identifiers
ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/ncomms12992