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Genomic and oncogenic preference of HBV integration in hepatocellular carcinoma

Genomic and oncogenic preference of HBV integration in hepatocellular carcinoma

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_9037ae5413474dd6bc6a7cc68bd5d357

Genomic and oncogenic preference of HBV integration in hepatocellular carcinoma

About this item

Full title

Genomic and oncogenic preference of HBV integration in hepatocellular carcinoma

Publisher

London: Nature Publishing Group UK

Journal title

Nature communications, 2016-10, Vol.7 (1), p.12992-12992, Article 12992

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Hepatitis B virus (HBV) can integrate into the human genome, contributing to genomic instability and hepatocarcinogenesis. Here by conducting high-throughput viral integration detection and RNA sequencing, we identify 4,225 HBV integration events in tumour and adjacent non-tumour samples from 426 patients with HCC. We show that HBV is prone to inte...

Alternative Titles

Full title

Genomic and oncogenic preference of HBV integration in hepatocellular carcinoma

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_9037ae5413474dd6bc6a7cc68bd5d357

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_9037ae5413474dd6bc6a7cc68bd5d357

Other Identifiers

ISSN

2041-1723

E-ISSN

2041-1723

DOI

10.1038/ncomms12992

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