Folic Acid Antimetabolites (Antifolates): A Brief Review on Synthetic Strategies and Application Opp...
Folic Acid Antimetabolites (Antifolates): A Brief Review on Synthetic Strategies and Application Opportunities
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Publisher
Basel: MDPI AG
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Language
English
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Publisher
Basel: MDPI AG
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Contents
Antimetabolites of folic acid represent a large group of drugs and drug candidates, including those for cancer chemotherapy. In this current review, the most common methods and approaches are presented for the synthesis of therapeutically significant antimetabolites of folic acid, which are Methotrexate (MTX), Raltitrexed (Tomudex, ZD1694), Pralatr...
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Full title
Folic Acid Antimetabolites (Antifolates): A Brief Review on Synthetic Strategies and Application Opportunities
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TN_cdi_doaj_primary_oai_doaj_org_article_903a2a0ca2054021bba44c85cea5aab8
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_903a2a0ca2054021bba44c85cea5aab8
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ISSN
1420-3049
E-ISSN
1420-3049
DOI
10.3390/molecules27196229
