Pre-activation of autophagy impacts response to olaparib in prostate cancer cells
Pre-activation of autophagy impacts response to olaparib in prostate cancer cells
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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Poly (ADP-ribose) polymerase 1 (PARP1) plays an essential role in DNA repair and is targeted by anticancer therapies using PARP inhibitors (PARPi) such as olaparib. PARPi treatment in prostate cancer (PC) is currently used as a monotherapy or in combination with standard therapies (hormonotherapy) in clinical trials for patients with DNA damage res...
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Pre-activation of autophagy impacts response to olaparib in prostate cancer cells
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TN_cdi_doaj_primary_oai_doaj_org_article_90493fedb1da4a0c9ce515338e9d1823
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_90493fedb1da4a0c9ce515338e9d1823
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ISSN
2399-3642
E-ISSN
2399-3642
DOI
10.1038/s42003-022-03210-5
