Development of a skin- and neuro-attenuated live vaccine for varicella
Development of a skin- and neuro-attenuated live vaccine for varicella
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Author / Creator
Wang, Wei , Pan, Dequan , Fu, Wenkun , Ye, Xiangzhong , Han, Jinle , Yang, Lianwei , Jia, Jizong , Liu, Jian , Zhu, Rui , Zhang, Yali , Liu, Che , Ye, Jianghui , Selariu, Anca , Que, Yuqiong , Zhao, Qinjian , Wu, Ting , Li, Yimin , Zhang, Jun , Cheng, Tong , Zhu, Hua and Xia, Ningshao
Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Contents
Varicella caused by the primary infection of varicella-zoster virus (VZV) exerts a considerable disease burden globally. Current varicella vaccines consisting of the live-attenuated vOka strain of VZV are generally safe and effective. However, vOka retains full neurovirulence and can establish latency and reactivate to cause herpes zoster in vaccin...
Alternative Titles
Full title
Development of a skin- and neuro-attenuated live vaccine for varicella
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TN_cdi_doaj_primary_oai_doaj_org_article_9066b971d3e843a9a0bd9d71281bfdf9
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_9066b971d3e843a9a0bd9d71281bfdf9
Other Identifiers
ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-022-28329-1
