Surface frustration re-patterning underlies the structural landscape and evolvability of fungal orph...
Surface frustration re-patterning underlies the structural landscape and evolvability of fungal orphan candidate effectors
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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Pathogens secrete effector proteins to subvert host physiology and cause disease. Effectors are engaged in a molecular arms race with the host resulting in conflicting evolutionary constraints to manipulate host cells without triggering immune responses. The molecular mechanisms allowing effectors to be at the same time robust and evolvable remain...
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Surface frustration re-patterning underlies the structural landscape and evolvability of fungal orphan candidate effectors
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TN_cdi_doaj_primary_oai_doaj_org_article_906f45af7b6a47169bcd31e0f4f07d7f
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_906f45af7b6a47169bcd31e0f4f07d7f
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ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-023-40949-9
