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Therapeutic potential of oleic acid supplementation in myotonic dystrophy muscle cell models

Therapeutic potential of oleic acid supplementation in myotonic dystrophy muscle cell models

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_90b2edade99644b7abd7de2526c613a2

Therapeutic potential of oleic acid supplementation in myotonic dystrophy muscle cell models

About this item

Full title

Therapeutic potential of oleic acid supplementation in myotonic dystrophy muscle cell models

Publisher

England: BioMed Central Ltd

Journal title

Biological research, 2024-05, Vol.57 (1), p.29-29, Article 29

Language

English

Formats

Publication information

Publisher

England: BioMed Central Ltd

More information

Scope and Contents

Contents

We recently reported that upregulation of Musashi 2 (MSI2) protein in the rare neuromuscular disease myotonic dystrophy type 1 contributes to the hyperactivation of the muscle catabolic processes autophagy and UPS through a reduction in miR-7 levels. Because oleic acid (OA) is a known allosteric regulator of MSI2 activity in the biogenesis of miR-7...

Alternative Titles

Full title

Therapeutic potential of oleic acid supplementation in myotonic dystrophy muscle cell models

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_90b2edade99644b7abd7de2526c613a2

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_90b2edade99644b7abd7de2526c613a2

Other Identifiers

ISSN

0717-6287,0716-9760

E-ISSN

0717-6287

DOI

10.1186/s40659-024-00496-z

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