Wnt activation as a therapeutic strategy in medulloblastoma
Wnt activation as a therapeutic strategy in medulloblastoma
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Author / Creator
Manoranjan, Branavan , Venugopal, Chitra , Bakhshinyan, David , Adile, Ashley A. , Richards, Laura , Kameda-Smith, Michelle M. , Whitley, Owen , Dvorkin-Gheva, Anna , Subapanditha, Minomi , Savage, Neil , Tatari, Nazanin , McKenna, Dillon , Bassey-Archibong, Blessing , Winegarden, Neil , Hallett, Robin , Provias, John P. , Yarascavitch, Blake , Ajani, Olufemi , Fleming, Adam , Bader, Gary D. , Pugh, Trevor J. , Doble, Bradley W. and Singh, Sheila K.
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
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Publication information
Publisher
London: Nature Publishing Group UK
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More information
Scope and Contents
Contents
Medulloblastoma (MB) is defined by four molecular subgroups (Wnt, Shh, Group 3, Group 4) with Wnt MB having the most favorable prognosis. Since prior reports have illustrated the antitumorigenic role of Wnt activation in Shh MB, we aimed to assess the effects of activated canonical Wnt signaling in Group 3 and 4 MBs. By using primary patient-derive...
Alternative Titles
Full title
Wnt activation as a therapeutic strategy in medulloblastoma
Authors, Artists and Contributors
Author / Creator
Venugopal, Chitra
Bakhshinyan, David
Adile, Ashley A.
Richards, Laura
Kameda-Smith, Michelle M.
Whitley, Owen
Dvorkin-Gheva, Anna
Subapanditha, Minomi
Savage, Neil
Tatari, Nazanin
McKenna, Dillon
Bassey-Archibong, Blessing
Winegarden, Neil
Hallett, Robin
Provias, John P.
Yarascavitch, Blake
Ajani, Olufemi
Fleming, Adam
Bader, Gary D.
Pugh, Trevor J.
Doble, Bradley W.
Singh, Sheila K.
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Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_90b86d3d0f9c41078f2e0a70337929d5
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_90b86d3d0f9c41078f2e0a70337929d5
Other Identifiers
ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-020-17953-4
