Targeting monoamine oxidase A-regulated tumor-associated macrophage polarization for cancer immunoth...
Targeting monoamine oxidase A-regulated tumor-associated macrophage polarization for cancer immunotherapy
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Author / Creator
Wang, Yu-Chen , Wang, Xi , Yu, Jiaji , Ma, Feiyang , Li, Zhe , Zhou, Yang , Zeng, Samuel , Ma, Xiaoya , Li, Yan-Ruide , Neal, Adam , Huang, Jie , To, Angela , Clarke, Nicole , Memarzadeh, Sanaz , Pellegrini, Matteo and Yang, Lili
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
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Publisher
London: Nature Publishing Group UK
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Contents
Targeting tumor-associated macrophages (TAMs) is a promising strategy to modify the immunosuppressive tumor microenvironment and improve cancer immunotherapy. Monoamine oxidase A (MAO-A) is an enzyme best known for its function in the brain; small molecule MAO inhibitors (MAOIs) are clinically used for treating neurological disorders. Here we obser...
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Full title
Targeting monoamine oxidase A-regulated tumor-associated macrophage polarization for cancer immunotherapy
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TN_cdi_doaj_primary_oai_doaj_org_article_90dbc47fa143484c89dae7f6960677f0
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_90dbc47fa143484c89dae7f6960677f0
Other Identifiers
ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-021-23164-2
