Single-cell and spatial sequencing identifies senescent and germinal tumor cells in adamantinomatous...
Single-cell and spatial sequencing identifies senescent and germinal tumor cells in adamantinomatous craniopharyngiomas
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England: BioMed Central Ltd
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Language
English
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England: BioMed Central Ltd
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Adamantinomatous craniopharyngioma (ACP) is a clinically aggressive tumor without effective treatment method. Previous studies proposed a paracrine tumorigenesis model, in which oncogenic β-catenin induces senescence in pituitary stem cells and the senescent cells lead the formation of paracrine tumors through secretion of pro-tumorigenic factors....
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Full title
Single-cell and spatial sequencing identifies senescent and germinal tumor cells in adamantinomatous craniopharyngiomas
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TN_cdi_doaj_primary_oai_doaj_org_article_91567842c447491bae7db4588ea86465
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_91567842c447491bae7db4588ea86465
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ISSN
2045-3701
E-ISSN
2045-3701
DOI
10.1186/s13578-024-01299-1
