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Phosphorylation of insulin receptor substrates (IRS-1 and IRS-2) is attenuated following cecal ligat...

Phosphorylation of insulin receptor substrates (IRS-1 and IRS-2) is attenuated following cecal ligat...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_918aea2b23df48e4a6b5643377a11c98

Phosphorylation of insulin receptor substrates (IRS-1 and IRS-2) is attenuated following cecal ligation and puncture in mice

About this item

Full title

Phosphorylation of insulin receptor substrates (IRS-1 and IRS-2) is attenuated following cecal ligation and puncture in mice

Publisher

England: Springer

Journal title

Molecular Medicine, 2023-08, Vol.29 (1), p.106-106, Article 106

Language

English

Formats

Publication information

Publisher

England: Springer

More information

Scope and Contents

Contents

Sepsis is characterized as an insulin resistant state. However, the effects of sepsis on insulin's signal transduction pathway are unknown. The molecular activity driving insulin signaling is controlled by tyrosine phosphorylation of the insulin receptor β-subunit (IRβ) and of insulin receptor substrate molecules (IRS) -1 and IRS-2.
Cecal ligati...

Alternative Titles

Full title

Phosphorylation of insulin receptor substrates (IRS-1 and IRS-2) is attenuated following cecal ligation and puncture in mice

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_918aea2b23df48e4a6b5643377a11c98

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_918aea2b23df48e4a6b5643377a11c98

Other Identifiers

ISSN

1528-3658,1076-1551

E-ISSN

1528-3658

DOI

10.1186/s10020-023-00703-9

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