α-tubulin detyrosination fine-tunes kinetochore-microtubule attachments
α-tubulin detyrosination fine-tunes kinetochore-microtubule attachments
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Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Contents
Post-translational cycles of α-tubulin detyrosination and tyrosination generate microtubule diversity, the cellular functions of which remain largely unknown. Here we show that α-tubulin detyrosination regulates kinetochore-microtubule attachments to ensure normal chromosome oscillations and timely anaphase onset during mitosis. Remarkably, detyros...
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Full title
α-tubulin detyrosination fine-tunes kinetochore-microtubule attachments
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TN_cdi_doaj_primary_oai_doaj_org_article_920deb434b9b43b78cca1c970eb4ae62
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_920deb434b9b43b78cca1c970eb4ae62
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ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-024-54155-8
