A high throughput screen for next-generation leads targeting malaria parasite transmission
A high throughput screen for next-generation leads targeting malaria parasite transmission
About this item
Full title
Author / Creator
Delves, Michael J. , Miguel-Blanco, Celia , Matthews, Holly , Molina, Irene , Ruecker, Andrea , Yahiya, Sabrina , Straschil, Ursula , Abraham, Matthew , León, María Luisa , Fischer, Oliver J. , Rueda-Zubiaurre, Ainoa , Brandt, Jochen R. , Cortés, Álvaro , Barnard, Anna , Fuchter, Matthew J. , Calderón, Félix , Winzeler, Elizabeth A. , Sinden, Robert E. , Herreros, Esperanza , Gamo, Francisco J. and Baum, Jake
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
Formats
Publication information
Publisher
London: Nature Publishing Group UK
Subjects
More information
Scope and Contents
Contents
Spread of parasite resistance to artemisinin threatens current frontline antimalarial therapies, highlighting the need for new drugs with alternative modes of action. Since only 0.2–1% of asexual parasites differentiate into sexual, transmission-competent forms, targeting this natural bottleneck provides a tangible route to interrupt disease transm...
Alternative Titles
Full title
A high throughput screen for next-generation leads targeting malaria parasite transmission
Authors, Artists and Contributors
Author / Creator
Miguel-Blanco, Celia
Matthews, Holly
Molina, Irene
Ruecker, Andrea
Yahiya, Sabrina
Straschil, Ursula
Abraham, Matthew
León, María Luisa
Fischer, Oliver J.
Rueda-Zubiaurre, Ainoa
Brandt, Jochen R.
Cortés, Álvaro
Barnard, Anna
Fuchter, Matthew J.
Calderón, Félix
Winzeler, Elizabeth A.
Sinden, Robert E.
Herreros, Esperanza
Gamo, Francisco J.
Baum, Jake
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_920f37303ca446e0a2ceaa2cbd0d76bf
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_920f37303ca446e0a2ceaa2cbd0d76bf
Other Identifiers
ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-018-05777-2