Mesenchymal stem cells empower T cells in the lymph nodes via MCP-1/PD-L1 axis
Mesenchymal stem cells empower T cells in the lymph nodes via MCP-1/PD-L1 axis
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Author / Creator
He, Yifan , Qu, Yan , Meng, Bowen , Huang, Weiying , Tang, Jianxia , Wang, Runci , Chen, Zetao , Kou, Xiaoxing and Shi, Songtao
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
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Publication information
Publisher
London: Nature Publishing Group UK
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Scope and Contents
Contents
Mesenchymal stem cells (MSCs) are a type of immunosuppressive stromal cell found in multiple tissues and organs. However, whether MSCs possess immunosupportive characteristics remains unclear. In this study, we showed that the lymph nodes contain immunosupportive MSCs. They produce and secrete a high level of MCP-1 to promote T-cell proliferation a...
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Full title
Mesenchymal stem cells empower T cells in the lymph nodes via MCP-1/PD-L1 axis
Authors, Artists and Contributors
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Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_921e4a937c004e8fb6677ebb1a23cbfd
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_921e4a937c004e8fb6677ebb1a23cbfd
Other Identifiers
ISSN
2041-4889
E-ISSN
2041-4889
DOI
10.1038/s41419-022-04822-9
