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SARS-CoV-2 infection induces adaptive NK cell responses by spike protein-mediated induction of HLA-E...

SARS-CoV-2 infection induces adaptive NK cell responses by spike protein-mediated induction of HLA-E...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_922fdbe1e53a41a29cccf93946fdf801

SARS-CoV-2 infection induces adaptive NK cell responses by spike protein-mediated induction of HLA-E expression

About this item

Full title

SARS-CoV-2 infection induces adaptive NK cell responses by spike protein-mediated induction of HLA-E expression

Publisher

United States: Taylor & Francis Ltd

Journal title

Emerging microbes & infections, 2024-12, Vol.13 (1), p.2361019

Language

English

Formats

Publication information

Publisher

United States: Taylor & Francis Ltd

More information

Scope and Contents

Contents

HLA-E expression plays a central role for modulation of NK cell function by interaction with inhibitory NKG2A and stimulatory NKG2C receptors on canonical and adaptive NK cells, respectively. Here, we demonstrate that infection of human primary lung tissue with SARS-CoV-2 leads to increased HLA-E expression and show that processing of the peptide Y...

Alternative Titles

Full title

SARS-CoV-2 infection induces adaptive NK cell responses by spike protein-mediated induction of HLA-E expression

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_922fdbe1e53a41a29cccf93946fdf801

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_922fdbe1e53a41a29cccf93946fdf801

Other Identifiers

ISSN

2222-1751

E-ISSN

2222-1751

DOI

10.1080/22221751.2024.2361019

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