Differential methylation of enhancer at IGF2 is associated with abnormal dopamine synthesis in major...
Differential methylation of enhancer at IGF2 is associated with abnormal dopamine synthesis in major psychosis
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Publisher
London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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Impaired neuronal processes, including dopamine imbalance, are central to the pathogenesis of major psychosis, but the molecular origins are unclear. Here we perform a multi-omics study of neurons isolated from the prefrontal cortex in schizophrenia and bipolar disorder (n = 55 cases and 27 controls). DNA methylation, transcriptomic, and genetic-ep...
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Full title
Differential methylation of enhancer at IGF2 is associated with abnormal dopamine synthesis in major psychosis
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TN_cdi_doaj_primary_oai_doaj_org_article_92406a1645fa465a86fc451c78740010
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_92406a1645fa465a86fc451c78740010
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ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-019-09786-7
