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Iron restriction inside macrophages regulates pulmonary host defense against Rhizopus species

Iron restriction inside macrophages regulates pulmonary host defense against Rhizopus species

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_929e08b851964a52b6dd9b6ff495bee8

Iron restriction inside macrophages regulates pulmonary host defense against Rhizopus species

About this item

Full title

Iron restriction inside macrophages regulates pulmonary host defense against Rhizopus species

Publisher

London: Nature Publishing Group UK

Journal title

Nature communications, 2018-08, Vol.9 (1), p.3333-17, Article 3333

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Mucormycosis is a life-threatening respiratory fungal infection predominantly caused by
Rhizopus
species. Mucormycosis has incompletely understood pathogenesis, particularly how abnormalities in iron metabolism compromise immune responses. Here we show how, as opposed to other filamentous fungi,
Rhizopus
spp. establish intracellular per...

Alternative Titles

Full title

Iron restriction inside macrophages regulates pulmonary host defense against Rhizopus species

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_929e08b851964a52b6dd9b6ff495bee8

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_929e08b851964a52b6dd9b6ff495bee8

Other Identifiers

ISSN

2041-1723

E-ISSN

2041-1723

DOI

10.1038/s41467-018-05820-2

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